Hi All, just signed up here!
I’ve read my eyes to burning red on color, spaces, profiles, management. Fascinating and hugely complicated! I bump this older thread as there are a few things I still can’t get my head around related to this discussion. 
I have a ThinkPad T61 laptop with a 1440 x 900 screen calibrated with Spyder3Pro. Win XP Pro SP3. My issue/question is only about colors on screen.
I shoot images in RAW sRGB > then Process in Lightroom (that uses PhotoPro internally) > then export to JPG sRGB in 100% quality. I find it very frustrating that a lot of images look a little or very different when viewed in Windows IE or the file viewer. The Firefox browser supports color management and I pointed Firefox to my monitor profile and images are rendered identical to Lightroom and Photoshop.
Coming to my question; the monitor calibration/profile works throughout the system. For Windows and for ‘color aware’ apps like Lightroom and - in this case - Firefox. So what causes the different colors viewing one and the same JPG file???
I’ve been cracking my head over this and it drives me nuts… 
Richard.