HQ RIP Settings for Printing target

Hello;
We have and Harlequin Based RIP and we want to print our Target to create profile for our Press.

Below is our RIP settings:
img34.picoodle.com/img/img34/4/7 … 637f17.jpg

As you see By Default this setting is our RIP “No ColorManagement” Default.

1- Which items we should check and which one shouldn’t?
I am really doubtful about “Overprint Process Colors” item at first, and so on for next items, what it is and what it do?

2-What really mean “Overprint Gray Images”?

Regards.